Gepotidacin and nitrofurantoin demonstrate similar efficacy in reducing symptom severity and restoring daily function in women with uncomplicated UTI.

The novel investigational oral antibiotic gepotidacin was efficacious and safe for the treatment of uncomplicated urinary tract infections, with activity against common uropathogens. Gepotidacin, a ...

Most urinary tract infections (UTIs) are bacterial infections, and treatment is often with antibiotics. Nitrofurantoin (Macrobid) is often the first choice, but there are other options. UTIs can ...

Gepotidacin is an oral, first-in-class triazaacenaphthylene antibiotic that inhibits bacterial DNA replication by blocking 2 different type II topoisomerase enzymes. Study participants were randomly ...

Review shows lower odds of symptomatic UTI episodes in children with history of recurrent UTIs with nitrofurantoin, cranberry. (HealthDay News) — For children with a history of recurrent urinary tract ...

Uncomplicated urinary tract infections remain a common and costly condition in the United States, with effective treatment complicated by recurrence and antibiotic resistance. In a recent AJMC Peer ...

Gepotidacin -- a first-in-class oral antibiotic -- appeared effective and safe for the treatment of uncomplicated urinary tract infections (UTIs) in a pair of large, phase III non-inferiority studies.

Many women with uncomplicated UTI willing to delay antibiotics Daily antibiotic use came out on top when compared with several other strategies for managing recurrent urinary tract infections (UTIs).

Cranberry products (compared with the control group) and nitrofurantoin (compared with the control, trimethoprim-sulfamethoxazole, or trimethoprim groups) led to lower odds of symptomatic UTI episodes ...