As is the case with most everything in the body, when it comes to glutamate, it is all about balance. Hence, the problem occurs when we have too much or too little glutamate. * Glutamate, which is excitatory, needs to balance with GABA, which is calming. * Consequently, an imbalance between the two can cause issues with sleep, anxiety, or focus. * Furthermore, research shows that kids with autism tend to have too much glutamate and not enough GABA. * Likewise, if your child has PANS or PANDAS, t